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JAK/STAT signaling is required for dilp8 expression in wounded discs. (A and B) Anti-BrdU staining in C48P fragments of (A) WT or (B) dilp8MI00727 homozygote. (C and D) In situ hybridization with dilp8 probe. (C) The up-regulation of dilp8 in WT C24P. (D) The dilp8 up-regulation was not observed in the hop3 C24P fragment. In all images, anterior is to the left, and dorsal is up. Yellow arrowheads indicate the fragmented positions. (Scale bar: 100 μm.)
