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. 2015 Mar 14;34(9):1214–1230. doi: 10.15252/embj.201489920

Figure 2. Che-1 regulates mTOR activity in response to cellular stress.

Figure 2

  • A WB analysis with the indicated Abs of TCEs from HCT116 treated with I.R. (20 Gy) (left), hypoxia (1% O2) (center), or 2DOG (25 mM) (right).
  • B, C WB analysis with the indicated Abs of TCEs from HCT116 cells with siRNA GFP (siControl) or siRNA Che-1 (siChe-1) and treated with hypoxia (B), I.R. (C, left), or 2DOG (C, right).
  • D WB analysis of TCEs from HCT116 p53−/− cells treated or not with hypoxia (1% O2) for 16 h.

Source data are available online for this figure.