Table 1. PML patients' characteristics.

CLINICAL CHARACTERISTICS OF 49 PML PATIENTS
Mean Age, y (range)	54.51 (21-89)
Gender M:F	33 (67.3 %):16 (32.7 %)
CSF PCR diagnosis	39 (79.6 %)
Histologic diagnosis	10 (20.4 %)
Underlying immunosuppression
HIV infection	19 (38.8 %)
Hematologic malignancy*	13 (26.5 %)
Hematologic disease- other†	7 (14.3 %)
Autoimmune disease‡	6 (12.2 %)
Other§	4 (8.2 %)
IRIS at the time of MRI	20 (40.8 %)
PML-S:PML-P	26 (53.1 %):23 (46.9 %)
HIV+ PML-S	13 (73%)
HIV- PML-S	12 (40%)

Abbreviations: PML = progressive multifocal leukoencephalopathy; PCR = polymerase chain reaction; HIV = human immunodeficiency virus; IRIS = immune reconstitution inflammatory syndrome; PML-S = PML-survivors; PML-P = PML-progressors

^*Chronic lymphocytic leukemia (n=9), non-Hodgkin lymphoma (n=2), NK cell leukemia (n=1), follicular center cell lymphoma (n=1)

^†Idiopathic lymphocytopenia (n=2), lymphomatoid granulomatosis (n=1), common variable immunodeficiency (n=1), Waldenstrom macroglobulinemia (n=2), Good syndrome (n=1)

^‡Multiple sclerosis treated with natalizumab (n=3), lupus erythematosus (n=1), dermatomyositis (n=1), rheumatoid arthritis (n=1)

^§brainstem glioma (n=1), cirrhosis (n=2), lung transplant (n=1)