Table 2. Occurrence of HCS in all PML subpopulations.

	HCS+	HCS -
Total number of patients	30	19
HIV+ patients	13	6
HIV- patients: total	17	13
Multiple sclerosis	3	0
Hematologic malignancies	7*	6**
Hematologic disease other	4†	3††
Auto-immune disease	1‡	2‡‡
Other	2§	2§§

Abbreviations: HCS= hyperintense cortical signal; PML = progressive multifocal leukoencephalopathy; HIV = human immunodeficiency virus

^*Chronic lymphocytic leukemia (n=5), non-Hodgkin lymphoma (n=1), follicular center cell lymphoma (n=1)

^**Chronic lymphocytic leukemia(n=4), non-Hodgkin lymphoma(n=1), NK cell leukemia(n=1)

^†Good syndrome(n=1), Idiopathic lymphocytopenia(n=2), lymphomatoid granulomatosis(n=1)

^††Waldenstrom macroglobulinemia(n=2), common variable immunodeficiency(n=1)

^‡lupus erythematosus(n=1)

^‡‡dermatomyositis(n=1), rheumatoid arthritis(n=1)

^§brainstem glioma(n=1), lung transplant(n=1)

^§§cirrhosis(n=2)