Table 4.
Top ATC Class Counts in NDF-RT and DrugBank
| NDF-RT | DrugBank | |||
|---|---|---|---|---|
| ATC Class Name | DDI | drugs | DDI | drugs |
| Antibiotics | 709 | 22 | 744 | 25 |
| Anticholinesterases | 25 | 4 | 411 | 7 |
| Fluoroquinolones | 401 | 11 | 335 | 14 |
| Hydantoin derivatives | 266 | 4 | 406 | 4 |
| Macrolides | 443 | 6 | 502 | 9 |
| Non-selective monoamine reuptake inhibitors | 311 | 10 | 736 | 10 |
| Other antidepressants | 309 | 11 | 457 | 10 |
| Protease inhibitors | 1130 | 11 | 751 | 11 |
| Protein kinase inhibitors | 759 | 19 | 389 | 20 |
| Selective immunosuppressants | 307 | 13 | 150 | 14 |
| Selective serotonin reuptake inhibitors | 341 | 6 | 380 | 6 |
| Triazole derivatives | 427 | 4 | 502 | 4 |
| Vitamin K antagonists | 292 | 3 | 427 | 3 |
*Boldface values indicate the ten top categories in each source.