Table 6.
Top DDI Pairs found in Prescription Data
| Drug pair | Freq | DrugBank DDI | NDF-RT DDI |
|---|---|---|---|
| Amlodipine-Simvastatin | 76980 | X | |
| Glipizide-Metoprolol | 15469 | X | X |
| atorvastatin-Fenofibrate | 14897 | X | X |
| Fenofibrate-Simvastatin | 14060 | X | X |
| Albuterol-Metoprolol | 14030 | X | |
| Insulin Glargine-Metoprolol | 13492 | X | |
| Metoprolol-Sertraline | 13311 | X | |
| atorvastatin-Diltiazem | 13218 | X | X |
| Digoxin-Furosemide | 12958 | X | |
| Lisinopril-Triamterene | 12399 | X | X |
| cyclobenzaprine-Tramadol | 12211 | X | |
| Diltiazem-Metoprolol | 11738 | X | |
| Oxycodone-Sertraline | 11710 | X | |
| Diltiazem-Simvastatin | 11484 | X | X |
| Alprazolam-Fluoxetine | 11194 | X | |
| Sertraline-Trazodone | 11066 | X | |
| Amoxicillin-Ethinyl Estradiol | 11044 | X | |
| Lisinopril-Spironolactone | 10248 | X | X |
| Clonazepam-Fluoxetine | 10149 | X | |
| Fenofibrate-rosuvastatin | 9954 | X | X |
| Clonidine-Metoprolol | 9827 | X | X |
| Hydralazine-Metoprolol | 9556 | X | |
| duloxetine-Trazodone | 9236 | X | |
| clopidogrel-pantoprazole | 9177 | X | |
| Escitalopram-Metoprolol | 8396 | X | |
| Levofloxacin-Prednisone | 8335 | X | |
| Escitalopram-Oxycodone | 8228 | X | |
| Citalopram-Trazodone | 8081 | X | |
| Citalopram-Oxycodone | 8016 | X | |
| Metoprolol-salmeterol | 7703 | X | |
| Atenolol-Glipizide | 7597 | X | X |
| Fluoxetine-Trazodone | 7579 | X | |
| carvedilol-Digoxin | 7517 | X | |
| Fluoxetine-Oxycodone | 7508 | X | |
| carvedilol-Insulin Glargine | 7496 | X | |
| Citalopram-Metoprolol | 7474 | X | |
| Escitalopram-Trazodone | 7421 | X | |
| Alprazolam-Omeprazole | 7339 | X |