Table 3.
Multivariate logistic regression analysis of baseline factors and their association with outcome
Factor | Survival to hospital discharge | Good neurological outcome | ||||
---|---|---|---|---|---|---|
OR | P | 95% CI | OR | P | 95% CI | |
Male gender | 1.34 | 0.04* | 1.01–1.78 | 1.24 | 0.16 | 0.92–1.67 |
Age (per year) | 0.96 | <0.001* | 0.95–0.97 | 0.96 | <0.001* | 0.95–0.97 |
Witnessed arrest | 1.88 | <0.001* | 1.34–2.66 | 2.30 | <0.001* | 1.57–3.37 |
Bystander CPR | 1.29 | 0.06 | 0.99–1.66 | 1.28 | 0.08 | 0.98–1.67 |
Presumed cardiac cause of arrest | 2.16 | <0.001* | 1.40–3.31 | 2.51 | <0.001* | 1.54–4.08 |
Time to ROSC (per minute) | 0.95 | <0.001* | 0.95–0.96 | 0.95 | <0.001* | 0.94–0.96 |
Initial shockable rhythm | 3.95 | <0.001* | 2.90–5.38 | 4.84 | <0.001* | 3.41–6.88 |
Comorbidities | ||||||
Coronary disease | 0.90 | 0.46 | 0.69–1.19 | 0.86 | 0.30 | 0.65–1.14 |
COPD | 0.68 | 0.049* | 0.47–1.00 | 0.71 | 0.11 | 0.47–1.08 |
Neurological disease | 0.63 | 0.045* | 0.40–0.99 | 0.57 | 0.03* | 0.35–0.93 |
Obesity (body mass index > 35) | 0.69 | 0.08 | 0.45–1.05 | 0.65 | 0.06 | 0.42–1.02 |
Diabetes (insulin dependent) | 0.59 | 0.04* | 0.36–0.98 | 0.81 | 0.42 | 0.48–1.37 |
Alcohol or drug abuse | 0.98 | 0.92 | 0.66–1.45 | 0.92 | 0.69 | 0.61–1.39 |
A total of 1,494 of the 1,667 patients had complete data and were included in the analysis. A cerebral performance category of 1 or 2 at hospital discharge is considered a good neurological outcome. * P <0.05. CI, confidence interval; COPD, chronic obstructive pulmonary disease CPR, cardiopulmonary resuscitation; ROSC, return of spontaneous circulation; OR, odds ratio.