Table 2.
Patients at high risk in primary prevention
| Complex intervention A n = 675 | Simple intervention B n = 649 | A vs. B | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean FU | 95% CI | Mean FU | 95% CI | Difference/Odds ratio | 95% CI | p | ICC | p | |
| CVR | 13.0% | 12.5%-13.6% | 12.5% | 11.9%-13.1% | Δ = 0.5% | -0.3%-1.3% | 0.197 | 0.029 | 0.004 |
| RR systolic [mmHg] | 138.0 | 136.4-139.7 | 137.3 | 135.6-139.1 | Δ = 0.7 | -1.7-3.1 | 0.563 | 0.082 | <0.001 |
| RR diastolic [mmHg] | 80.5 | 79.6-81.4 | 80.0 | 79.0-80.9 | Δ = 0.5 | -0.8-1.8 | 0.461 | 0.078 | <0.001 |
| Control rate RR < 140/90 | 46.7% | 40.4%-53.1% | 46.9% | 40.3%-53.5% | OR = 0.99 | 0.68-1.45 | 0.966 | 0.128 | <0.001 |
| Control rate RR < 160/95 | 86.8% | 83.1%-90.6% | 88.9% | 85.4%-92.3% | OR = 0.82 | 0.51-1.31 | 0.405 | 0.141 | <0.001 |
| Cholesterol [mg/dl] | 221.9 | 219.1-224.6 | 220.9 | 218.1-223.7 | Δ = 1.0 | -3.0-4.93 | 0.634 | 0.015 | 0.085 |
| Current smoker | 12.0% | 9.7%-14.4% | 14.4% | 11.9%-17.0% | OR = 0.71 | 0.44-1.16 | 0.171 | 0.093 | 0.019 |
| ASS | 21.4% | 19.1%-23.7% | 23.9% | 21.0%-26.8% | OR = 0.67 | 0.37-1.19 | 0.172 | 0.206 | <0.001 |
| Statins | 23.3% | 19.7%-26.9% | 19.4% | 15.8%-23.0% | OR = 1.52 | 0.89-2.62 | 0.128 | 0.206 | <0.001 |
Outcomes at follow up in subpopulation at high CVR (10-year mortality ≥ 5%), but no manifest CVD (complete cases), adjusted for baseline and taking cluster effects into account by use of a mixed model.