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. 2015 May 11;5:10172. doi: 10.1038/srep10172

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Binding isotherms for 4-MP-PTOX and 4-TG-PTOX validated by isothermal titration calorimetry (ITC). For all panels, the top isotherm represents the heat of dissolution of compounds in solution, and the second isotherm represents the fragment binding titration.