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. 2015 May 11;5:10172. doi: 10.1038/srep10172

Table 1. IC50 values of the compounds against tumor cells and normal human cells.

  Cytotoxic activity (IC50, μM)a
Compound BGC-823b A549b HepG2b HL-7720b
4-MP-PTOX 8.72 ± 3.15 1.12 ± 0.35 1.14 ± 1.07 11.30 ± 0.57
4-TG-PTOX 4.40 ± 1.55 0.57 ± 0.92 0.30 ± 0.34 13.51 ± 2.41
PTOX 18.32 ± 2.22 20.15 ± 2.75 8.36 ± 1.42 4.31 ± 1.46
Colchicines 12.17 ± 1.26 12.23 ± 0.76 13.22 ± 0.88 6.42 ± 1.03
Nocodazole 38.89 ± 3.12 27.44 ± 2.92 18.35 ± 3.71 8.51 ± 1.73

aStandard deviation (SD) of triplicate samples was calculated from three independent samples, mean ± SD (n = 3)

bMTT methods, drug exposure was for 48 h.