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. 2015 May 11;5:10096. doi: 10.1038/srep10096

Table 2. Multivariate-adjusted ordinal logistic regression analyses for odds ratios of progressive liver injury, insulin resistance and incident diabetes for plasma IP-10.

Analysis Progressive liver injury, insulin resistance, and incident diabetes
  Odds ratio P Value 95% Confidence Interval
Univariate
 ln IP-10, pg/ml 31.02 <0.001 9.15–105.18
 
Multivariate
 Model 1 32.62 <0.001 9.01–118.05
 Model 2 9.90 0.005 1.98–49.58
 Model 3 7.84 0.014 1.51–40.82

Model 1 is adjusted for IP-10 plus age and sex. Model 2 is adjusted for the variables in model 1 plus traditional risk factors (SBP, BMI, fasting glucose, total cholesterol and HOMA-IR); Model 3 is adjusted for the variables in model 2 plus nontraditional risk factors (ALT, endotoxin, hs-CRP, leptin and MDA). The Nagelkerke pseudo R2 of model 3 was 0.836. Logarithmic transformation (ln) of IP-10, BMI, fasting glucose, HOMA-IR, ALT, endotoxin, hs-CRP, leptin and MDA was used to normalize the distributions for multivariate analysis.

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