Cytochrome P450 (CYP) eicosanoid temporal concentration profiles and trajectory patterns. (A) Raw population values of dihydroxyeicosatetraenoic acid (DHET) cerebrospinal fluid (CSF) concentrations (ng/mL) from 269 patients up to 14 days after hemorrhage are shown. (B) DHET CSF concentration versus time from hemorrhage (days) in high (filled circles, n=65 (24.2%)), moderate (open circles, n=159 (59.1%)), and low (X, n=45 (16.7%)) concentration groups as identified by trajectory analysis is shown. Concentration data are presented as geometric mean with 95% confidence interval.