Table 1.
Quantitative analysis of medulloblastoma cell transmigration
| Transmigration of medulloblastoma cells | |||
|---|---|---|---|
| Med8A (%) | D425 (%) | ||
| Fibronectin | control | 100 | 100 |
| 1 Gy photon IR | 74 ± 1.4 (*) | 103 ± 23.4 (ns) | |
| 2 Gy photon IR | 61 ± 17 (*) | 71 ± 9.3 (*) | |
| 10 Gy photon IR | 51 ± 4.2 (*) | 53 ± 2.9 (*) | |
| 0.5 GyE 12C IR | 57 ± 18.4 (*) | 79 ± 1.4 (ns) | |
| 1 GyE 12C IR | 30 ± 1.4 (*) | 66 ± 14 (ns) | |
| 3 GyE 12C IR | 25 ± 4.2 (*) | 51 ± 4.2 (*) | |
| Collagen I | control | 100 | 100 |
| 1 Gy photon IR | 102 ± 21.2 (ns) | 89 ± 16.5 (ns) | |
| 2 Gy photon IR | 91.5 ± 17.7 (ns) | 69.3 ± 9.1 (*) | |
| 10 Gy photon IR | 97 ± 23 (ns) | 55 ± 21.2 (*) | |
| 0.5 GyE 12C IR | 49 ± 9.2 (*) | 81 ± 10.6 (*) | |
| 1 GyE 12C IR | 38 ± 4.2 (*) | 59 ± 5.7 (*) | |
| 3 GyE 12C IR | 33 ± 4.9 (*) | 24 ± 25 (*) | |
| Collagen IV | control | 100 | 100 |
| 1 Gy photon IR | 62 ± 7.1 (*) | 109 ± 12.7 (ns) | |
| 2 Gy photon IR | 57 ± 7.1 (*) | 96 ± 44.5 (ns) | |
| 10 Gy photon IR | 43 ± 26.9 (*) | 74 ± 1.4 (*) | |
| 0.5 GyE 12C IR | 16 ± 4.2 (*) | 54 ± 7.1 (*) | |
| 1 GyE 12C IR | 15 ± 2.1 (*) | 49 ± 9.2 (*) | |
| 3 GyE 12C IR | 13 ± 4.2 (*) | 46 ± 4.2 (*) | |
Asterisk = statistical significance, P < 0.05, ns = absence of statistical significance, P > 0.05.