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. Author manuscript; available in PMC: 2016 May 7.
Published in final edited form as: Cell. 2015 May 7;161(4):737–749. doi: 10.1016/j.cell.2015.03.031

FIGURE 4. Memory CD8 T cell migration is compartmentally restricted within NLT.

FIGURE 4

P14 immune chimeras conjoined to naive C57BL/6 mice (as in figure 3) were analyzed 30 days after parabiosis surgery. (A) The fraction of P14 CD8 T cells that are resident in the indicated tissue compartments, small intestine (SI), large intestine (LI), stomach (ST), epithelium (IEL), lamina propria (LP), submucosa (S.M.), muscularis externa (M.E.). (B) Representative thymus images in immune and naive parabionts. P14 CD8 T cells (red), DAPI (green), cytokeratin 5 (blue), scale bar= 50μm. (C) Percent of P14 CD8 T cells that are resident in the thymus medulla and cortex. (D) Percent of i.v. Ab+ P14 CD8 T cells that are resident within the kidney and liver. n=3, representative of 9 mouse pairs from 3 independent experiments. Graphs show mean and SEM, (See also Figure S2).