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Explaining VPA C/D ratio use with VPA concentrations from a published case [29].
| Formulation | VPA dose (mg/day) | Concentration (μg/mL) | C/D ratio | C/D ratio × 1000 |
|---|---|---|---|---|
| ECDVNa | 1000 | 112 | 0.112 | 112 |
| ECDVNa | 750 | 87 | 0.116 | 116 |
| ECDVNa | 500 | 66 | 0.132 | 132 |
| ECDVNa | 500 | 64 | 0.128 | 128 |
C/D: concentration-to-dose; ECDVNa: divalproex sodium enterocoated; VPA: valproic acid.
