Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 30;21:86–95. doi: 10.12659/MSMBR.893608

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Med Sci Monit, 2015

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License

PMC Copyright notice

Oxidative stress assays. (A) p21 overexpression (p21+) significantly upregulated GSH-Px activity, while p21 silencing (p21–) significantly downregulated GSH-Px activity. UVB irradiation significantly upregulated GSH-Px activity in control (CON) cells but significantly downregulated GSH-Px activity in UVB-irradiated p21-overexpressing (UVB-p21+) and UVB-irradiated p21-silenced (UVB-p21–) cells. (B) Both p21 overexpression (p21+) and p21 silencing (p21–) significantly raised H₂O₂ content. UVB irradiation significantly raised H₂O₂ content in UVB-irradiated control (UVB-CON), UVB-irradiated p21-overexpressing (UVB-p21+) and UVB-irradiated p21-silenced (UVB-p21–) cells. (C) Both p21 overexpression (p21+) and p21 silencing (p21–) significantly raised MDA content. UVB irradiation significantly raised MDA content in UVB-irradiated control (UVB-CON), UVB-irradiated p21-overexpressing (UVB-p21+) and UVB-irradiated p21-silenced (UVB-p21–) cells. (D) Both p21 overexpression (p21+) and p21 silencing (p21–) significantly reduced SOD activity. UVB irradiation significantly reduced SOD activity in UVB-irradiated control (UVB-CON), UVB-irradiated p21-overexpressing (UVB-p21+) and UVB-irradiated p21-silenced (UVB-p21–) cells. * p<0.05 vs. CON, ^# p<0.05 vs. p21+, ^@ p<0.05 vs. p21–, ^& p<0.05 vs. UVB-CON.