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. Author manuscript; available in PMC: 2015 May 11.
Published in final edited form as: Bioorg Med Chem Lett. 2014 Jul 24;24(17):4158–4161. doi: 10.1016/j.bmcl.2014.07.049

Figure 1.

Figure 1

2mFo-Fc election density maps for TS active site of ChTS-DHFR: FdUMP: compound 1 complex (A) with MTX and NADPH in the DHFR site (contour level at 1.0 σ) (B) with compound 1 and NADPH in the DHFR site (contour level at 1.3 σ).