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. 2015 Apr 27;2015:796380. doi: 10.1155/2015/796380

Table 1.

FGFR protein expressions on immunohistochemical analysis and clinical outcomes in GC.

n Definition of positivity Positive case % Relation to clinicopathological factors Relation to survival Reference
FGFR1 222 Scoring system of intensity + extensity 29 T, N, M, stage Worse [19]

FGFR2 950 2+ or 3+, >50% 31 T, N, M, stage Worse [22]
222 Scoring system of intensity + extensity 51 T, N, M, stage Worse [19]
136 Stronger than normal epithelium 31 T, peritoneal Dissemination, diffuse type Worse [20]
49 Stronger than normal epithelium 41 Stage
Undifferentiated type
Worse [21]

FGFR3 222 Scoring system of intensity + extensity 64 NA NA [19]

FGFR4 222 Scoring system of intensity + extensity score 79 T, N, M, stage Worse [19]
94 3+, >10% 38 NA Worse [23]

T: tumor depth; N: lymph-node metastasis; M: distant metastasis; NA: not assisted.