Table 2.
Vessel characteristic | LETO group | OLETF group |
---|---|---|
Gastrocnemius feed artery | ||
Passive diameter (µm) | 289 ± 12 | 292 ± 13 |
Preconstriction (%) | ||
Insulin | 41 ±2 | 43 ± 3 |
Insulin + tezosentan | 41 ±4 | 42 ± 3 |
Dilatation in response to tezosentan (% possible) | 12 ±4 | 28 ± 5* |
Soleus feed artery | ||
Passive diameter (µm) | 185 ± 12 | 209 ± 6† |
Preconstriction (%) | ||
Insulin | 52 ±4 | 51 ± 3 |
Insulin + tezosentan | 45 ±3 | 48 ± 4 |
Dilatation in response to tezosentan (% possible) | 11 ± 13 | 31 ± 8 |
Data are means ± SEM.
P < 0.05 versus LETO.
P = 0.06 versus LETO.