Table 2. Dock Score of four fluoroquinolones for wild type and mutant DNA Gyrase complex of S. Typhi.
CFX | LFX | DFX | MFX | |
---|---|---|---|---|
Wild Type | 76.24 | 78.16 | 71.43 | 80.59 |
Ser83Phe | 63.14 | 74.57 | 64.48 | 74.40 |
Ser83Tyr | 65.83 | 72.35 | 64.04 | 72.62 |
Asp87Tyr | 62.35 | 76.08 | 68.99 | 75.28 |
Asp87Gly | 59.10 | 73.95 | 66.59 | 71.79 |