Table 3.

Multivariable Adjusted Associations between covariates and 30-day mortality

	OR	95% CI	P
RDW-no.(%)
≤13.3%	1	Reference
13.3–14%	1.19	1.08–1.30	<0.001
14–14.7%	1.28	1.16–1.42	<0.001
14.7–15.8%	1.69	1.53–1.86	<0.001
>15.8%	2.61	2.37–2.86	<0.001
Age (per 1 year)	1.02	1.01–1.02	<0.001
Gender
Male	1	Reference
Female	1.02	0.97–1.08	0.4
Race
White	1	Reference
Non-White	1.06	0.99–1.14	0.08
Patient Type
Medical	1	Reference
Surgical	0.65	0.61–0.69	<0.001
Deyo-Charlson Index
0	1	Reference
1	1.69	1.43–1.99	<0.001
2	2.14	1.83–2.51	<0.001
3	2.21	1.88–2.59	<0.001
4	2.42	2.05–2.85	<0.001
≥5	2.09	1.78–2.45	<0.001
Creatinine
≤1.0 mg/dl	1.06	0.98–1.14	0.2
1.0–1.3 mg/dl	1	Reference
1.3–2.0 mg/dl	1.20	1.10- 1.31	<0.001
>2.0 mg/dl	1.14	1.03–1.27	0.01
Hematocrit (%)
≤30	1.03	0.93–1.13	0.6
30–33	1.12	1.01–1.24	0.03
33–36	1.09	0.99–1.21	0.07
36–39	1.01	0.91–1.11	0.9
39–42	0.93	0.84–1.03	0.2
>42	1	Reference
White Blood Cell
<4 × 103/mm3	2.03	1.79–2.30	<0.001
4–12 × 103/mm3	1	Reference
>12 × 103/mm3	1.80	1.69–1.90	<0.001
Blood Urea Nitrogen
<10 mg/dl	0.81	0.73–0.91	<0.001
10–20 mg/dl	1	Reference
20–40 mg/dl	1.29	1.20–1.39	<0.001
>40 mg/dl	1.72	1.55–1.90	<0.001
MCV (per 1 femtoliter)	1.03	1.03–1.04	<0.001
Sepsis*	1.92	1.80–2.05	<0.001
AMI*	1.02	0.95–1.10	0.5
CHF*	0.93	0.87–0.99	0.03
CABG*	0.34	0.28–0.40	<0.001
Transfusions
0 units	1	Reference
1 units	1.18	1.05–1.34	0.008
2 units	1.09	0.97–1.23	0.2
3 units	1.07	0.91–1.25	0.4
≥4 units	1.14	1.05–1.25	0.003

Note: Estimates for each variable are adjusted for all other variables in the table. Transfusions variable indicates RBC transfusions from 48 hours prior to critical care initiation throughout the ICU stay.

^*Referent is absence of condition.