Table 2. Sensitivity analysis results.
Items | Studies | Sample size | Tests for heterogeneity | Analysis model | Test for overall effect | RR/WMD | Favors | ||
---|---|---|---|---|---|---|---|---|---|
RA/GA | I2 | P* | Z | P* | 95%CI | ||||
Operative Time(min) | [7–14] | 398/400 | 85% | <0.00001 | Random | 2.63 | 0.009 | -5.55 [-9.68,-1.41] | RA |
Tramadol demand(mg) | [7–9,11,12,14] | 345/344 | 96% | <0.00001 | Random | 5.64 | <0.00001 | -59.68 [-80.41,-38.94] | RA |
Complications | |||||||||
IOH | [8,11] | 144/142 | 41% | 0.19 | Fixed | 2.56 | 0.01 | 2.24 [1.21,4.15] | GA |
Nausea/Vomiting | [8,10–12,14] | 318/318 | 0% | 0.92 | Fixed | 4.23 | <0.0001 | 0.39 [0.25,0.60] | RA |
Fever | [8,11,12] | 194/192 | 5% | 0.35 | Fixed | 1.30 | 0.19 | 0.75 [0.48,1.16] | RA |
Blood Transfusion | [9–13] | 193/190 | 0% | 0.85 | Fixed | 0.36 | 0.72** | 0.90 [0.52,1.56] | RA |
Grade I POC | [10–12] | 132/128 | 46% | 0.16 | Fixed | 0.88 | 0.38 | 0.69 [0.30,1.58] | RA |
Grade II POC | [10–12] | 132/128 | 0% | 0.99 | Fixed | 0.56 | 0.58** | 0.85 [0.48,1.50] | RA |
≥Grade III POC | [11,12] | 108/102 | 0% | 0.78 | Fixed | 1.09 | 0.27** | 0.44 [0.10,1.91] | RA |
Total POC | [10–12] | 132/128 | 5% | 0.35 | Fixed | 1.45 | 0.15 | 0.74 [0.49,1.11] | RA |
Hospital Stay(d) | [8–10,12] | 192/198 | 49% | 0.12 | Fixed | 7.73 | <0.00001 | -0.59[-0.74,-0.44] | RA |
Stone-Free Rate | [8–12] | 234/182 | 0% | 0.48 | Fixed | 0.42 | 0.68 | 1.02 [0.93,1.12] | RA |
RA: regional anesthesia GA: general anesthesia RR: relative risk WMD: weighted mean difference CI: confidence interval IOH: intraoperative hypotension POC: postoperative complications
* P<0.05 was considered statistically significant.
**originally significant before nRCTs excluded.