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. 2015 May 7;145(2):288–299. doi: 10.1111/imm.12447

Figure 4.

Figure 4

Antiretroviral therapy- and Env immunization-associated changes in CCR7 expression in circulatory and rectal tissue-resident natural killer (NK) cells. Freshly isolated peripheral blood mononuclear cells (PBMCs) and rectal tissue-derived lymphocytes were analysed for their CCR7 surface expression levels on CD56+, CD16+ and double negative (DN) NK cell subsets. (a) Representative dot plots and overlaying histograms showing CCR7 expression patterns in different NK cell subsets in PBMCs (top) and rectal (bottom) samples. (b–g) Percentage of CCR7+ NK cells in each subset in PBMCs (top, b–d) and rectal (bottom, e, f) samples. Data reported are means ± SEM. *P < 0·05 and **P < 0·01 indicate statistically significant differences in each group when compared with Pre (week 0) by repetitive one-way analysis of variance followed by Dunn's multiple comparisons test.