Table 2.
Lewy pathology density scores in 10 brain regions of the studied patients grouped by Unified stages [mean ± standard errors (subject numbers)].
| Unified stages/brain regions | I | IIa | IIb | III | IV |
|---|---|---|---|---|---|
| Olfactory bulb | 1.71 ± 0.19 (11) | 1.40 ± 0.68 (5) | 3.31 ± 0.18 (16) | 2.17 ± 0.24 (30) | 2.92 ± 0.20 (39) |
| Substantia nigra | 0.00 ± 0.00 (11) | 0.50 ± 0.29 (5) | 0.50 ± 0.18 (16) | 2.27 ± 0.18 (33) | 2.67 ± 0.13 (42) |
| Pons | 0.00 ± 0.00 (11) | 0.75 ± 0.48 (4) | 0.25 ± 0.18 (12) | 2.74 ± 0.18 (34) | 2.78 ± 0.16 (40) |
| Medulla | 0.00 ± 0.00 (11) | 1.00 ± 0.70 (4) | 0.83 ± 0.21 (12) | 2.88 ± 0.19 (32) | 2.81 ± 0.17 (42) |
| Amygdala | 0.00 ± 0.00 (11) | 0.60 ± 0.40 (5) | 3.60 ± 0.13 (15) | 3.44 ± 0.11 (32) | 3.73 ± 0.09 (41) |
| Trans‐entorhinal cortex | 0.00 ± 0.00 (11) | 0.40 ± 0.40 (5) | 2.93 ± 0.31 (14) | 2.36 ± 0.17 (33) | 3.31 ± 0.13 (42) |
| Cingulate cortex | 0.00 ± 0.00 (11) | 0.20 ± 0.20 (5) | 0.60 ± 0.13 (15) | 1.88 ± 0.13 (32) | 3.11 ± 0.12 (44) |
| Temporal cortex | 0.00 ± 0.00 (11) | 0.00 ± 0.00 (5) | 0.33 ± 0.13 (15) | 0.97 ± 0.05 (32) | 2.50 ± 0.12 (44) |
| Parietal cortex | 0.00 ± 0.00 (11) | 0.00 ± 0.00 (5) | 0.06 ± 0.06 (15) | 0.77 ± 0.09 (34) | 1.73 ± 0.11 (45) |
| Frontal cortex | 0.00 ± 0.00 (11) | 0.00 ± 0.00 (5) | 0.06 ± 0.06 (15) | 0.77 ± 0.07 (34) | 1.67 ± 0.11 (45) |