Skip to main content
. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Diabetes Metab Res Rev. 2015 Mar 6;31(4):346–359. doi: 10.1002/dmrr.2636

FIGURE 1.

FIGURE 1

Figure 1. Deaths in infected mice. CD-1 mice were fed a chow diet until they were 5 weeks old. At that time, the mice were placed on either a high fat diet or a matched regular diet for the remainder of the experiment. Fifty-three days later (designated day 0), some of the mice (now 13 weeks old) were infected with Trypanosoma cruzi. Deaths were recorded on each day from day 0 to day 70. Note that on day 35 (marked by the vertical line), some animals were sacrificed for more in-depth study. The height of each bar represents the deaths that occurred on that day, expressed as a percentage of the total animals in that group on day 0 (or animals in that group on day 35 post-sacrifice). No deaths occurred in the uninfected mice. Starting 20 days prior to infection, some mice were given metformin once daily (50 mg/kg by gavage) for the remainder of the experiment.