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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Appl Immunohistochem Mol Morphol. 2015 Sep;23(8):580–589. doi: 10.1097/PAI.0000000000000118

FIGURE 1.

FIGURE 1

CCR8 mRNA levels as determined by quantitative real-time PCR (qRT-PCR) in whole sections from frozen tumor tissue. Values were normalized to GAPDH expression and expressed as fold change compared to the mean value of cases lacking DUSP22 rearrangements. Horizontal lines indicate means for each group and points indicate individual patients. (a) CCR8 expression was significantly higher in ALCLs with DUSP22 rearrangements than in non-rearranged cases. (b) No significant difference in CCR8 expression was observed among subtypes; though there was a trend toward higher expression in ALK-negative ALCL and pcALCL, this was mostly attributable to cases with DUSP22 rearrangements (red points). Black points are cases without DUSP22 rearrangements.