Figure 2. eRNA-induced release of pro-inflammatory mediators in human monocytes.
A) Monocytes were treated under normoxia in the absence (Control) or presence of different concentrations of eRNA and at various time points as indicated, followed by analysis of TNF-α in corresponding cell supernatants. B) Following 6 h incubation of monocytes in the absence (Control) or presence of eRNA, the release of IL-6, CCL3 and CCL4 was quantified by ELISA in cell supernatants. Values represent mean ± SD (n=5); *p<0.05, #p<0.001 vs Control.