Figure 1.

Concentrations of sputum biomarkers (LTB₄, 8-isoprostane, MPO activity, IL-8) and purulence scores for patients chronically colonized with Haemophilus influenzae (yes) and in patients not chronically colonized with H. influenzae (no).

Notes: The graphs show levels of these parameters at stable phase (using the mean of each parameter at all stable visits). The data are presented as the median (interquartile range) and *P≤0.05, **P≤0.01, ***P≤0.001 for comparisons between colonized and non-colonized patients.

Abbreviations: H. influenzae, Haemophilus influenzae; LTB₄, leukotriene B₄; MPO, myeloperoxidase; IL, interleukin.