Table 1.
Chronically colonized with H. influenzae N=10 | Not chronically colonized with H. influenzae n=21 | |
---|---|---|
Females/males, n | 6/4 | 9/12 |
Age, years | 68 (63–70) | 65 (57–73) |
Smokers/ex-smokers, n | 2/8 | 6/15 |
Pack-years | 39 (32–44) | 40 (35–50) |
Exacerbates, n | 7 | 11 |
GOLD 1, n | 0 | 1 |
GOLD 2, n | 2 | 6 |
GOLD 3, n | 6 | 9 |
GOLD 4, n | 2 | 5 |
Notes: All patients had FEV1/FVC <0,7, and GOLD stages were defined as GOLD 1 (FEV1 ≥80% of predicted normal), GOLD 2 (50≥FEV1,80%p), GOLD 3 (30≥ FEV1 <50%p) and GOLD 4 (FEV1 <30%p). Exacerbates = number of patients that exacerbate during the study.
Abbreviations: FEV1, forced expiratory volume in 1 second; GOLD, Global Initiative for Chronic Obstructive Lung Disease; H. influenzae, Haemophilus influenzae; %p, % of predicted normal.