Figure 1.

Dihydromyricetin protects mice against CCl₄-induced liver injury. Mice were treated with CCl₄ (1 mL/kg body weight and 1:3 diluted in corn oil) to induce acute liver injury, and then orally administered with DHM (80 mg/kg body weight and diluted in CMC-Na) 2 h after CCl₄ injection, once per day for 4 d. Control mice were treated with an equal volume of CMC-Na. Subsequently, serum ALT, AST, albumin, SOD, IL-1β, IL-6, TNF-α and liver SOD were measured at indicated time points and determined as described in materials and methods. A: Serum ALT; B: Serum AST; C: Serum Albumin; D: Serum SOD; E: Liver SOD; F: Serum IL-1β; G: Serum IL-6; H: Serum TNF-α. Values represent mean ± SE (n = 6). ^aP < 0.05 and ^bP < 0.01 vs control, respectively.