Figure 2.
Dihydromyricetin accelerates liver regeneration in liver injury mice. Immunohistochemical staining for proliferating cell nuclear antigen (PCNA) was carried out as previously described. Data showed PCNA staining liver sections in the mice without (A) or with dihydromyricetin (DHM) treatment (B) on day 2 after CCl4 injection. The control group showed few PCNA+ hepatocytes in centrilobular areas, but DHM administration resulted in numerous PCNA+ hepatocytes surrounding the edge of hepatocellular necrosis. (C) The numbers of PCNA+ cells. At least six 12 mm2 tissue sections were counted for each mouse. Values represent mean ± SE (n = 6), bP < 0.01 vs control.