Table 1.
Patient characteristics at baseline n (%)
|
HBeAg-negative |
HBeAg-positive |
|||
| Asian | Non-Asian | Asian | Non-Asian | |
| n = 102 | n = 186 | n = 115 | n = 113 | |
| Male | 71 (70) | 144 (77) | 60 (52)b | 84 (73) |
| Age (yr, mean ± SD) | 44 ± 9.4 | 44 ± 10.9 | 34 ± 9.7 | 33 ± 11.9 |
| BMI (kg/m2, mean ± SD) | 24.1 ± 3.1b | 26.4 ± 4.5 | 23.0 ± 3.5b | 25.1 ± 5.5 |
| HBV DNA (log10 copies/mL, mean ± SD) | 6.5 ± 1.4a | 6.9 ± 1.3 | 8.4 ± 1.1b | 8.9 ± 1.0 |
| Median ALT, U/L (Q1, Q3) | 73 (45, 115) | 103 (67, 140) | 90 (56, 144) | 118 (88, 196) |
| Normal ALT1 | 17 (17)b | 12 (6.5) | 10 (9) | 5 (4) |
1
Normal ALT ≤ 34 U/L for females; ≤ 43 U/L for males.
a
P ≤ 0.05,
b
P ≤ 0.01, vs non-Asian patients. ALT: Alanine aminotransferase; BMI: Body mass index; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus; Q1: Quartile 1; Q3: Quartile 3.