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. 2014 Jul 16;7(1):33–40. doi: 10.2478/intox-2014-0006

Table 10.

Effect of Cypermethrin on Differential Leukocyte Count in Rattus norvegicus.

Cell type Treatment No. of days Control* Treatment % Change Significance
Range Mean±S.E. Range Mean±S.E.
Neutrophils Acute 1 24-28 26.0±0.78 23-27 25.28±1.23 -0.46 P>0.05
Subchronic 7 26-30 28.22±1.73 28-41 30.12±2.60 ±6.73 P<0.05
14 23-29 26.00±1.73 32-41 36.66±2.60 ±41 P<0.05
21 28-30 29.33±0.67 33-36 34.33±1.2 ±17.05 P<0.01
28 27-30 28.22±0.63 29-33 32.0±1.42 ±13.39 P<0.01
Recovery** 60 25-28 27.10±0.75 24-27 26.87±0.65 -0.52 P>0.05
Eosinophils Acute 1 2-4 3.30±0.75 2-5 4.04±0.64 ±32.89 P>0.05
Subchronic 7 2-3 2.21±0.47 1-3 2.46±0.07 ±11.31 P>0.05
14 1-3 1.93±0.86 2-4 2.34±0.98 ±21.24 P>0.05
21 1-3 2.00±0.54 1-3 2.00±0.54 - P>0.05
28 2-3 2.65±1.16 1-3 2.00±0.65 -24 P>0.05
Recovery** 60 2-4 2.28±0.64 1-3 1.69±0.81 -28.99 P>0.05
Lymphocytes Acute 1 65-73 70.08±0.57 67-72 70.68±1.31 -0.28 P>0.05
Subchronic 7 67-71 69.57±0.45 66-70 67.42±0.72 -3.09 P>0.05
14 67-72 71.40±1.64 58-63 61.0±0.89 -14.56 P>0.05
21 67-70 68.67±0.88 63-64 63.67±0.58 -7.06 P<0.01
28 66-70 69.13±0.65 63-68 64.25±1.63 -7.06 P<0.01
Recovery** 60 65-72 70.62±0.97 66-72 70.70±1.20 ±0.13 P>0.05
Monocytes Acute 1 00-01 0.68±0.35 0 0 0 No change
7 00 0 0 0 0 No change
Subchronic 14 0-1 0.62±0.33 1-2 1.03±0.74 ±0.53.73 P>0.05
21 0 0 0 0 0 No change
28 0 0 0 0 0 No change
Recovery** 60 0 0 0 0.73±0.03 - P>0.05
*

Controls were given groundnut oil only

**

Recovery group were given oil (a) and cypermethrin (b) treatment for 28 days and effects assessed after 60 days