Table 5.
Differences in the serum cytokine levels in the adult Tanzanian patients based on gender and mycobacterial culture from lymph nodes.
| Cytokine (pg/mL) | Male (n = 27) Median (range) |
Female (n = 34) Median (range) |
P value∗ | Culture positive (n = 13) Median (range) |
Culture negative (n = 48) Median (range) |
P value∗∗ |
|---|---|---|---|---|---|---|
| IFN-γ | 0.0 (0–42.8) | 0.0 (0–30.9) | 0.98 | 0.0 (0–22.4) | 0.0 (0–42.8) | 0.383 |
| TNF-α | 3.2 (0–352.5) | 11.8 (0–73) | 0.15 | 8.4 (0.5–352.5) | 12.4 (0–72.9) | 0.874 |
| GM-CSF | 35.2 (0–507) | 55.1 (0–457) | 0.96 | 35.2 (0–506.9) | 34.5 (0–457.7) | 0.864 |
| IL-1β | 72.6 (0–1338) | 5.7 (0–6305) | 0.51 | 0.0 (0–1338.8) | 66.5 (0–6305.4) | 0.746 |
| IL-2 | 0.0 (0–28) | 0.0 (0–19.8) | 0.31 | 0.0 (0–28.2) | 0.0 (0–19.8) | 0.193 |
| IL-4 | 0 (0–9.5) | 0 (0–18) | 0.30 | 0.0 (0–6.8) | 0.0 (0–18.5) | 0.360 |
| IL-5 | 1.5 (0–10) | 0.75 (0–6.4) | 0.16 | 1.0 (0–8.1) | 1.0 (0–10.0) | 0.465 |
| IL-6 | 46.4 (0–18979) | 55.5 (0–25781) | 0.80 | 46.4 (0–18979.1) | 55.6 (0–25781.5) | 0.825 |
| IL-8 | 362 (0–27670) | 419 (0–386577) | 0.70 | 638.2 (0–27670.3) | 366.4 (0–386578.0) | 0.486 |
| IL-10 | 0.0 (0–29) | 0.0 (0–22) | 0.96 | 0.0 (0–29.3) | 0.0 (0–22.8) | 0.513 |
| IL-12 | 0 (0–20.7) | 0.1 (0–37) | 0.03 | 0.3 (0–20.7) | 0.0 (0–37.8) | 0.029 |
| IL-15 | 0.0 (0–61) | 0.0 (0–25) | 0.77 | 0.6 (0–21.1) | 0.0 (0–61.4) | 0.223 |
| IL-17 | 0 (0–134) | 0 | 0.04 | 0.0 (0–26.1) | 0.0 (0–133.7) | 0.638 |
∗ P value for difference between males and females and ∗∗ P value for difference between culture positive and culture negative TB patients.