Table 4.

Antibiotic exposure by randomization group with subgroup analysis

	Control group	PCT/Pyuria group	P value a
	Median (IQR), days	Median (IQR), days
All patients (intention-to-treat)	(n = 64)	(n = 61)
Duration of initial antibiotic therapy	10.0 (7.0–11.0)	6.0 (4.0–8.0)	<0.001
Antibiotic exposure within 90 days	10.0 (7.0–16.0)	7.0 (5.0–14.0)	0.011
Per-protocol population	(n = 52)	(n = 44)
Duration of initial antibiotic therapy	10.0 (7.0–11.0)	6.0 (4.0–7.0)	<0.001
Antibiotic exposure within 90 days	10.0 (7.5–16.0)	7.0 (5.0–14.5)	0.025
Female patients	(n = 52)	(n = 43)
Duration of initial antibiotic therapy	9.0 (7.0–10.5)	5.0 (4.0–7.0)	<0.001
Antibiotic exposure within 90 days	10.0 (7.0–14.0)	7.0 (4.0–13.0)	0.022
Male patients	(n = 12)	(n = 18)
Duration of initial antibiotic therapy	11.0 (10.5–12.0)	6.5 (5.0–9.0)	0.003
Antibiotic exposure within 90 days	16.0 (11.0–21.0)	9.0 (6.0–19.0)	0.062
Inpatients	(n = 45)	(n = 45)
Duration of initial antibiotic therapy	10.0 (8.0–11.0)	7.0 (5.0–9.0)	<0.001
Antibiotic exposure within 90 days	11.0 (10.0–18.5)	8.5 (6.5–16.5)	0.023
Uncomplicated simple UTI	(n = 6)	(n = 2)
Duration of initial antibiotic therapy	1.0 (1.0–1.0)	0.5 (0.0–1.0)	0.127
Antibiotic exposure within 90 days	1.0 (1.0–1.0)	4.0 (1.0–7.0)	0.513
Complicated simple UTI	(n = 12)	(n = 16)
Duration of initial antibiotic therapy	7.0 (7.0–9.0)	4.0 (2.5–5.5)	0.005
Antibiotic exposure within 90 days	10.0 (8.0–12.0)	5.5 (3.0–14.0)	0.083
Uncomplicated febrile UTI/pyelonephritis	(n = 8)	(n = 9)
Duration of initial antibiotic therapy	7.0 (7.0–7.5)	4.0 (4.0–6.0)	0.009
Antibiotic exposure within 90 days	7.0 (7.0–10.5)	6.5 (4.0–11.0)	0.238
Complicated febrile UTI/pyelonephritis	(n = 34)	(n = 33)
Duration of initial antibiotic therapy	10.5 (10.0–11.0)	7.0 (6.0–9.0)	<0.001
Antibiotic exposure within 90 days	11.0 (10.0–18.0)	7.5 (6.5–13.5)	0.002

^aMann–Whitney U-test.

IQR, Interquartile range.