Table 1.
Relationship between FoxM1 expression from IHC and clinicopathological factors of 87 CRC patients
| Clinic parameters | Total | FoxM1 expression | χ 2 | P value | |
|---|---|---|---|---|---|
| None or low | High | ||||
| Age(years) | T=87 | N=35(40.2%) | N=52(59.8%) | ||
| <65 | 33(37.9%) | 15(45.5%) | 18(54.5%) | 0.604 | 0.437 |
| >=65 | 54(62.1%) | 20(37.0%) | 34(63.0%) | ||
| Gender | |||||
| Male | 42(48.3%) | 19(45.2%) | 23(54.8%) | 0.847 | 0.357 |
| Female | 45(51.7%) | 16(35.6%) | 29(64.4%) | ||
| Tumor size | |||||
| <5cm | 56(64.4%) | 20(35.7%) | 36(64.3%) | 1.333 | 0.248 |
| >=5cm | 31(35.6%) | 15(48.4%) | 16(51.6%) | ||
| Tumor location | |||||
| Right colon | 33(37.9%) | 11(33.3%) | 22(66.7%) | 1.052 | 0.305 |
| Left colon and rectum | 54(62.1%) | 24(44.4%) | 30(55.6%) | ||
| TNM Stage | |||||
| Stage I/II | 42(48.3%) | 19(45.2%) | 23(54.8%) | 0.847 | 0.357 |
| Stage III/IV | 45(51.7%) | 16(35.6%) | 29(64.4%) | ||
| Histological differentiation | |||||
| Well | 28(32.2%) | 12(42.9%) | 16(57.1%) | 1.873 | 0.392 |
| Moderate | 46(52.9%) | 20(43.5%) | 26(56.5%) | ||
| Poor | 13(14.9%) | 3(23.1%) | 10(76.9%) | ||
| Lymph node metastasis | |||||
| Yes | 47(54.0%) | 12(25.5%) | 35(74.5%) | 9.184 | 0.002*** |
| No | 40(56.0%) | 23(57.5%) | 17(42.5%) | ||
| Tumor recurrence | |||||
| Yes | 53(60.9%) | 15(28.3%) | 38(71.7%) | 8.025 | 0.005*** |
| No | 34(39.1%) | 20(58.8%) | 14(41.2%) | ||
***P < 0.001.