Table 4.
Subgroup analyses for sex and treatment with biologics
| Baseline | 1st wave | 2nd wave | ICC baseline vs. 1st wave | ICC baseline vs. 2nd wave | IC C 1st wave vs. 2nd wave | |
|---|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | ||||
| Category: subjective health status | ||||||
| How would you describe your current state of health? | ||||||
| Men | 2.5 ± 0.8 | 2.6 ± 1.1 | 2.7 ± 1.1 | 0.29 | 0.44 | 0.56 |
| Women | 2.6 ± 0.9 | 2.8 ± 1.1 | 2.8 ± 1.0 | 0.39 | 0.49 | 0.44 |
| Biologics as current medication | 2.6 ± 0.9 | 2.7 ± 1.1 | 2.7 ± 1.1 | 0.51 | 0.57 | 0.54 |
| No biologics as current medication | 2.6 ± 0.9 | 2.9 ± 1.1 | 2.8 ± 1.0 | 0.30 | 0.41 | 0.43 |
| Disease duration ≤3 years | 2.8 ± 0.8 | 2.8 ± 1.1 | 2.7 ± 0.8 | 0.45 | 0.50 | 0.50 |
| Disease duration 4 to 10 years | 2.7 ± 0.9 | 2.9 ± 1.2 | 3.0 ± 1.2 | 0.57 | 0.47 | 0.58 |
| Disease duration ≥11 years | 2.4 ± 1.0 | 2.8 ± 1.1 | 2.9 ± 0.9 | 0.41 | 0.60 | 0.32 |
| How would you describe your overall feeling of well-being at the present moment? | ||||||
| Men | 2.7 ± 1.0 | 2.6 ± 1.2 | 2.6 ± 0.9 | 0.63 | 0.32 | 0.48 |
| Women | 2.7 ± 1.1 | 2.7 ± 1.2 | 2.7 ± 1.1 | 0.35 | 0.40 | 0.39 |
| Biologics as current medication | 2.5 ± 1.0 | 2.6 ± 1.2 | 2.7 ± 1.2 | 0.32 | 0.29 | 0.38 |
| No biologics as current medication | 2.8 ± 1.2 | 2.7 ± 1.1 | 2.6 ± 0.9 | 0.42 | 0.45 | 0.42 |
| Disease duration ≤3 years | 2.8 ± 1.1 | 2.5 ± 1.1 | 2.6 ± 0.9 | 0.18 | 0.47 | 0.46 |
| Disease duration 4 to 10 years | 2.8 ± 0.9 | 2.8 ± 1.2 | 2.7 ± 1.0 | 0.57 | 0.53 | 0.29 |
| Disease duration ≥11 years | 2.6 ± 1.3 | 2.7 ± 1.1 | 2.8 ± 1.1 | 0.59 | 0.34 | 0.28 |
| How is your joint pain today? | ||||||
| Men | 3.0 ± 1.0 | 2.7 ± 1.0 | 2.9 ± 1.2 | 0.28 | 0.20 | 0.25 |
| Women | 2.9 ± 1.2 | 2.8 ± 1.1 | 2.8 ± 1.1 | 0.52 | 0.42 | 0.42 |
| Biologics as current medication | 2.7 ± 1.0 | 2.8 ± 1.2 | 2.9 ± 1.2 | 0.69 | 0.44 | 0.57 |
| No biologics as current medication | 3.0 ± 1.2 | 2.8 ± 1.1 | 2.9 ± 1.1 | 0.39 | 0.34 | 0.31 |
| Disease duration ≤3 years | 2.9 ± 1.2 | 2.6 ± 1.3 | 2.8 ± 1.2 | 0.25 | 0.23 | 0.64 |
| Disease duration 4 to 10 years | 2.7 ± 1.0 | 3.0 ± 1.2 | 3.0 ± 1.1 | 0.60 | 0.50 | 0.45 |
| Disease duration ≥11 years | 2.9 ± 1.3 | 2.7 ± 1.2 | 3.0 ± 1.0 | 0.48 | 0.20 | 0.22 |
| How happy are you today with the general state of your illness? | ||||||
| Men | 2.7 ± 1.2 | 2.6 ± 1.3 | 2.7 ± 1.4 | 0.24 | 0.46 | 0.65 |
| Women | 2.7 ± 1.2 | 2.7 ± 1.1 | 2.8 ± 1.2 | 0.38 | 0.38 | 0.41 |
| Biologics as current medication | 2.4 ± 1.0 | 2.7 ± 1.2 | 2.7 ± 1.3 | 0.52 | 0.41 | 0.48 |
| No biologics as current medication | 2.8 ± 1.3 | 2.6 ± 1.2 | 2.8 ± 1.2 | 0.28 | 0.39 | 0.46 |
| Disease duration ≤3 years | 2.6 ± 1.4 | 2.5 ± 1.2 | 2.5 ± 1.3 | 0.46 | 0.16 | 0.39 |
| Disease duration 4 to 10 years | 2.5 ± 1.0 | 2.9 ± 1.3 | 2.8 ± 1.2 | 0.47 | 0.47 | 0.73 |
| Disease duration ≥11 years | 2.9 ± 1.4 | 2.6 ± 1.1 | 2.9 ± 1.3 | 0.25 | 0.51 | 0.24 |
| Category: quality of life | ||||||
| To what extent is the quality of your life today influenced by the illness, rheumatoid arthritis? | ||||||
| Men | 3.0 ± 1.3 | 2.8 ± 1.5 | 2.6 ± 1.2 | 0.33 | 0.39 | 0.58 |
| Women | 3.2 ± 1.2 | 2.8 ± 1.2 | 2.6 ± 1.2 | 0.51 | 0.42 | 0.56 |
| Biologics as current medication | 3.1 ± 1.2 | 2.6 ± 1.2 | 2.7 ± 1.3 | 0.39 | 0.37 | 0.64 |
| No biologics as current medication | 3.2 ± 1.2 | 2.8 ± 1.3 | 2.7 ± 1.1 | 0.51 | 0.44 | 0.52 |
| Disease duration ≤3 years | 3.1 ± 1.1 | 2.3 ± 1.1 | 2.5 ± 1.0 | 0.03 | 0.07 | 0.21 |
| Disease duration 4 to 10 years | 3.1 ± 1.0 | 3.0 ± 1.3 | 2.8 ± 1.3 | 0.52 | 0.49 | 0.56 |
| Disease duration ≥11 years | 3.2 ± 1.3 | 2.6 ± 1.2 | 2.7 ± 1.2 | 0.48 | 0.53 | 0.62 |
SD – standard deviation; ICC - Intraclass correlation coefficient for one-way random single measures.
No statistically significant differences between men and women, between use of biologics and no biologics, and between disease duration subgroups were observed.