Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 30;14:97. doi: 10.1186/s12943-015-0368-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Trinh et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

DLX4 stimulates tumor angiogenesis and ascites formation in i.p. xenograft models of ovarian cancer by inducing iNOS. Female nude mice (n = 5 per group) were inoculated i.p. with equivalent numbers of cells (1 x 10⁶) of vector-control, +DLX4 and +DLX4 + shNOS2 ES2 lines and sacrificed at 20 days thereafter. (A) Volume of ascites. (B) Average numbers of microvessels were calculated in omental tumors by scoring five random 100x microscopic fields of CD34-stained tissue sections of each mouse. (C) Representative examples of CD34 staining in omental tumors. Bar, 100 μm.