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. 2015 Jan 23;26(3):549–558. doi: 10.1021/acs.bioconjchem.5b00028

Table 1. Tissue Distribution Data and Pharmacokinetic Parameters of Gd6L67Ga in Normal Balb/C Mice (n = 4)a.

  %ID/g
Organ 1 h 4 h 24 h
Blood 3.51 ± 0.22 2.63 ± 0.84 0.21 ± 0.06
Heart 1.21 ± 0.13 0.94 ± 0.40 0.21 ± 0.02
Lung 2.59 ± 0.5 1.78 ± 0.87 0.38 ± 0.09
Liver 1.39 ± 0.11 2.13 ± 0.81 1.39 ± 0.24
Kidney 101.32 ± 4.32 57.42 ± 17.29 43.90 ± 5.12
Spleen 0.73 ± 0.19 0.69 ± 0.07 0.42 ± 0.12
Muscle 0.27 ± 0.09 0.38 ± 0.13 0.08 ± 0.02
Fat 0.27 ± 0.10 0.27 ± 0.10 0.06 ± 0.02
Brain 0.08 ± 0.01 0.07 ± 0.02 0.02 ± 0.00
Two-Compartment Clearance Profile (min)
t1/2α 11.33 ± 1.31 t1/2β 438.37 ± 15.11
a

Data are presented as mean ± standard deviation.