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. 2015 May 12;5:10114. doi: 10.1038/srep10114

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Copyright © 2015, Macmillan Publishers Limited

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Apoptosis-related gene expression and correlation with chromosome euploidy in arrested cloned eight-cell embryos from different somatic cells. (A) Expression profiling of P53, Bax and Bcl-2 genes; ** P < 0.01; (B) Half of the embryos (50%) in the SCNT-S1 group, 100% of embryos in the SCNT-S2 group, and 60% of embryos in the SCNT-S3 group showed aneuploidy; (C) P53 gene expression levels were positively correlated with chromosome aneuploidy in cloned embryos; (D) Morphology was not correlated with chromosome aneuploidy in cloned embryos.