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. 2015 May 12;9:165. doi: 10.3389/fncel.2015.00165

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Copyright © 2015 Zhang, Chen, Ni, Guo, Lu, Liu, Li, Sun, Wang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lgr6-EGFP expression is restricted to the IPCs in the cochlea at P1. (A) At low magnification, only one row of Lgr6-EGFP-positive cells was detected, and Lgr6-EGFP was only expressed in the middle and basal turns in the cochlear epithelium at P1. (B) Immunostaining with an anti-Lgr6 antibody in wild-type cochlea showed that Lgr6 expression was restricted to the IPCs at P1. (C) The percentage of Lgr6-EGFP-positive IPCs (IPCs) at P1 and P3 (n = 4). (D) At P1, Lgr6-EGFP was expressed only in the IPCs in the middle and basal turns. IPCs, inner pillar cells.