Table 2.
Cox regression analysis for disease-free survival in TNBC
| Parameters | Univariate | Multivariate | |
|---|---|---|---|
| p-value | HR, 95% CI | p-value | |
| Age (≤50 years vs >50 years) | 0.12 | 2.18 (0.02-143.2) | 0.74 |
| Menopausal Status (Pre- vs Post-) | 0.15 | 0.80 (0.01-51.3) | 0.91 |
| Tumour size (pT1 vs pT2-T3) | 0.08 | 1.81 (0.45-7.14) | 0.39 |
| Lymph node status (pN0 vs pN+) | 0.2 | 1.25 (0.31-4.96) | 0.74 |
| Nuclear Grade (G1-G2 vs G3) | 0.08 | 0.66 (0.27-1.62) | 0.37 |
| Ki-67 (≤20% vs >20%) | 0.38 | 0.78 (0.27-2.26) | 0.66 |
| Lympho-vascular invasion (absence vs presence) | 0.17 | 1.68 (0.26-10.70) | 0.58 |
| Necrosis (absence vs presence) | 0.08 | 3.75 (0.69-20.15) | 0.12 |
| Intraductal carcinoma (absence vs presence) | 0.9 | 1.87 (0.43-8.10) | 0.40 |
| NLR (≤3 vs >3) | 0.002 | 5.15 (1.11 – 23.88) | 0.03 |
Table 2 shows a significant correlation between DFS and higher pre-treatment NLR.
Legend: NLR = Neutrophil to Lymphocyte Ratio; HR = hazard ratio; CI = confidence interval; TNBC = Triple Negative Breast Cancer.