Table 2.
Exposure levels, oxidative stress, and DNA damage in coke oven workers (COWs) and controls
| Parameters | Controls | Topside COWs | Other COWs |
|---|---|---|---|
| (n = 67) | (n = 51) | (n = 79) | |
| Exposure levels | |||
| 1-OHP(μmol/mol creatinine)a | 0.6 (0.2–1.9) | 6.5 (2.9–10.3)*** | 2.4 (1.1–5.7)*** |
| Oxidative stress | |||
| SOD (U/mL)a | 1068.5 (35.2) | 753.7 (60.9)*** | 821.8 (47.1)*** |
| GPx (U/mL)a | 84.2 (2.3) | 47.8 (5.6)*** | 55.1 (3.9)*** |
| MDA (nmol/mL)a | 3.9 (0.8) | 6.9 (1.4)*** | 6.7 (1.2)*** |
| DNA damage | |||
| MN frequency (‰)a | 2.2 (1.8) | 5.1 (4.7)*** | 4.6 (5.2)*** |
| 8-OH-dG(μmol/mol creatinine)b | 1.3 (0.8–1.8) | 2.3 (1.0–7.1)*** | 2.4 (0.7–6.9)*** |
*** P < 0.001 vs. control group.
aArithmetic mean (standard deviation).
bGeometric mean (95% confidence interval).