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| Strain | MIC | ||
|---|---|---|---|
| AmB, μg/ml | Radicicol, μM | TBH, mM | |
| BY4741/vector | 0.4 | 16 | 2 |
| pmp3Δ/vector | 0.05 | 8 | 2 |
| pmp3Δ/ScPMP3 | 1.6 | 16 | 2 |
| erg6Δ/vector | 1.6 | 2 | 0.5 |
MIC for AmB and radicicol was determined in SC-ura broth at 30°C. Sensitivity to oxidative stress was determined by dilution spotting on SC-ura agar medium with tert-butyl hydroperoxide (TBH) at 37°C. MIC is the concentration at which no growth was observed.
