Table 1.

Body weight change, food intake, water consumption, hematology parameters, liver enzymes, and serum hepcidin levels with standard deviations for each group at the end of the study (day 8)

	Control group	DSS group	DSS + IPC group	DSS + FS group	Significant differences (P<0.05)
Bodyweight change (g/week)	29.0±3.8	−16.5±2.4	−18.2±3.3	−28.8±5.5	Control > DSS ≈ DSS + IPC > DSS + FS
Food intake (g/week)	140.2±8.1	114.2±7.4	111.4±8.5	96.5±6.5	Control > DSS ≈ DSS + IPC > DSS + FS
Water consumption (mL/day)	31.1±2.0	25.9±3.9	28.7±4.3	27.9±3.4	Control > DSS = DSS + IPC > DSS + FS
Hematology parameters
Hb (g/dL)	14.4±0.5	10.9±0.2	10.7±0.4	10.1±0.3	Control > DSS ≈ DSS + IPC > DSS + FS
Serum iron (μg/dL)	264.4±22.3	147.9±15.8	189.6±15.3	170.2±18.7	Control > DSS + IPC ≈ DSS + FS > DSS
TIBC (μg/dL)	621.3±52.6	486.0±51.2	644.6±38.0	639.2±45.0	DSS + IPC ≈ DSS + FS ≈ control > DSS
TSAT (%)	42.5±1.6	30.4±1.8	29.4±1.7	26.6±1.7	Control > DSS ≈ DSS + IPC > DSS + FS
Liver enzymes
AST (UI/L)	96.5±17.1	136.3±18.0	151.8±24.7	162.8±25.0	Control < DSS ≈ DSS + IPC ≈ DSS + FS
ALT (UI/L)	40.2±5.5	61.2±5.5	80.4±7.4	87.3±5.4	Control < DSS < DSS + IPC ≈ DSS + FS
ALP (UI/L)	529.7±22.9	601.8±16.7	648.8±19.3	660.6±25.0	Control < DSS < DSS + IPC ≈ DSS + FS
Serum hepcidin (pg/mL)	12.1±0.9	18.6±2.0	22.6±3.9	37.9±4.5	Control < DSS + IPC ≈ DSS + FS < DSS

Notes: Data shown is mean ± standard deviation unless otherwise specified. The order of the groups shown in the last column indicates significant differences with P<0.05 for < and >, whereas ≈ denotes a nonsignificant difference.

Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; DSS, dextran sulfate sodium; FS, ferrous sulfate; Hb, hemoglobin; IPC, iron polymaltose complex; TIBC, total iron binding capacity; TSAT, transferrin saturation.