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. 2015 May 11;9:27–35. doi: 10.4137/JEN.S25057

Figure 3.

Figure 3

(A and B) Effect of morphine on the novel-object exploration test and horizontal locomotor activity during the test. Numbers of novel-object (a small binder clip with fold-back arms) exploration were recorded (A) with a simultaneous measurement of horizontal movement by Animex Auto (B) for five minutes. Values are shown as mean ± SEM (n = 13). *P < 0.05, compared with saline- or morphine plus naloxone-treated mice (post hoc Bonferroni–Dunn test). (C) Effects of morphine on the time spent in open arms in the elevated plus maze. Values are shown as mean ± SEM (n = 8). (D) Effects of morphine on marble-burying behavior in mice. Values are expressed as number of marbles buried by mice for 30 minutes (mean ± SEM, n = 10). ***P < 0.001, compared with saline-, naloxone-, or morphine plus naloxone-treated mice (post hoc Bonferroni–Dunn test).