Table 2.
Probabilities of carrying mutation in either BRCA1 or BRCA2 (Any BRCA), BRCA1, and BRCA2 for the proband in family 1s for varying age status of her aunt and grandmother.
| CARRIER PROBABILITIES FOR THE PROBAND | ||||||
|---|---|---|---|---|---|---|
| ANY BRCA | BRCA1 | BRCA2 | ||||
| Missing current ages for #4, #10, and #11, real affection ages for #8 and #6 resp. 63 and 58 | 0.0911 | – | 0.0410 | – | 0.0500 | – |
| Missing current ages for #4, #10, and #11, artificial affection ages for #8 and #6 resp. 35 and 32 | 0.4792 | ↑ | 0.2680 | ↑ | 0.2103 | ↑ |
| Missing current ages for #4, #10, and #11, missing affection ages for #8 and #6 | 0.1204 | ↑ | 0.0670 | ↑ | 0.0532 | ↑ |