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Probabilities of carrying mutation in either BRCA1 or BRCA2 (any BRCA), BRCA1, and BRCA2 for the proband in family 1b in different mastectomy scenarios.
| CARRIER PROBABILITIES FOR THE PROBAND | ||||||
|---|---|---|---|---|---|---|
| ANY BRCA | BRCA1 | BRCA2 | ||||
| No information (baseline) | 0.3827 | – | 0.0424 | – | 0.3402 | – |
| Mastectomy for ID #1 (proband) at age 53 | 0.4131 | ↑ | 0.0493 | ↑ | 0.3637 | ↑ |
| Mastectomy for ID #1 and 19 (uncle) at ages 53 and 89 | 0.4446 | ↑ | 0.0481 | ↑ | 0.3964 | ↑ |
