Table 2.
Significant average tract of interest results for the diffusion tensor indices.
| FA | MD | DR | DA | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TOI | aMCI-LLD | aMCI | LLD | aMCI-LLD | aMCI | LLD | aMCI-LLD | aMCI | LLD | aMCI-LLD | aMCI | LLD | ||||||||||||
| CN | aMCI | LLD | CN | LLD | CN | CN | aMCI | LLD | CN | LLD | CN | CN | aMCI | LLD | CN | LLD | CN | CN | aMCI | LLD | CN | LLD | CN | |
| Cingulum cing) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Cingulum (hipp) | - | - | - | - | - | - | ↑↑ | - | - | ↑ | - | ↑↑ | ↑↑ | - | - | ↑ | - | ↑↑ | ↑ | - | - | - | - | ↑ |
| Corpus Callosum | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ↑↑ |
| Fornix | - | - | - | ↓ | - | - | ↑↑ | - | - | - | - | ↑ | ↑↑ | - | - | - | - | ↑ | ↑↑ | - | - | - | - | ↑ |
| Uncinate Fasciculus | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ↑ |
Notes. Significant increases (red arrow) and decreases (blue arrow) are summarized, based on the ANCOVA and post-hoc analyses results (Bonferroni corrected; single arrow: p value <0.01; double arrows: p value < 0.0025).
Abbreviations: CN, cognitively normal; LLD, late-life depression; aMCI, amnestic mild cognitive impairment; aMCI-LLD, amnestic mild cognitive impairment with depression; ANCOVA, Analysis of covariance; TOIs, Tracts of interest.