Table 1. Sample Demographics.
| Schizophrenia Patients (n=48) | Healthy Volunteers (n=63) | Statistic | p-value | |
|---|---|---|---|---|
| Mean Age (SD) | 37.0 (10.7) | 37.6 (12.4) | t109=0.28 | 0.78 |
| Gender (M/F) | 35/13 | 39/24 | χ21=1.49 | 0.22 |
| Handedness (bilateral/left/right) | 1/6/41 | 1/5/57 | FET5 | 0.77 |
| Mean premorbid FSIQ1 estimate (SD) | 105.1 (9.5) | 113.3 (7.2) | t105= -5.05 | <0.0001 |
| Subject's Mean Years of Education (SD) | 13.3 (1.5) | 16.0 (1.9) | t100=-7.86 | <0.0001 |
| Mother's Mean Years of Education (SD) | 13.3 (3.0) | 13.8 (3.0) | t91=-0.83 | 0.41 |
| Father's Mean Years of Education (SD) | 14.6 (3.4) | 14.9 (3.6) | t91=-0.40 | 0.69 |
| Race (% Caucasian) | 66% | 75.8 | ||
| Race6 | FET | 0.20 | ||
| American Indian or Alaskan Native | 0 | 1 | ||
| Asian | 3 | 3 | ||
| Black or African American | 10 | 5 | ||
| White | 34 | 52 | ||
| SANS (global measures sum) | 7.49 (3.71) | |||
| SAPS (global measures sum) | 6.28 (2.68) | |||
| InterSePT suicidality scale (sum of 12 items) | 2.26 (3.18) | |||
| Calgary Depression Scale (total score) | 5.36 (5.04) | |||
| rs1625579 genotype (GG/GT/TT) | 0/9/39 | 2/15/46 | FET | 0.47 |
| SIRP Load 3 % Correct (SD) / Mean RT (SD)2,3 | ||||
| GG | 100 (0) / 6774 | |||
| GT | 89.6 (12.2) / 967 (235) | 97.4 (3.8) / 736 (110) | ||
| TT | 94.2 (8.5) / 784 (130) | 96.5 (4.8) / 696 (91) | ||
| Absolute Mean % (SD) left DLPFC Activation2 | ||||
| GG | … | -0.023 (0.242) | ||
| GT | 0.195 (0.380) | 0.075 (0.340) | ||
| TT | 0.298 (0.323) | 0.216 (0.250) |
1
FSIQ = Full Scale Intelligence Quotient; derived from the NAART (29)
2
Absolute means are provided for all three rs1625579 genotypes (GG, GT, and TT) though the analyses combine the less frequent GG and GT genotypes.
3
Response times were collected at 8 of the 9 sites (90 of 111 subjects).
4
No SD, only a single subject with response time.
5
FET = Fisher's Exact Test.
6
Race is missing for one patient and 2 controls.